Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKTLALAATAAVLMLSACSSGFGGEKEEEITQKTAKSSEKAIVPKYNISDSYYKMVLPFKAGKARGLTTEQ---LNT----RLDIDEFETGLMRLAQDSFSTDDYLFQEGQYLDEDTVLSWLARK-KTGSDLKKAEKEDKNFKNEGLNPALPSSGSTEEKNESSPIYLASML---EHDYLVRKDKNSIQLGGVMIGLALNS-VYYYREKTGDPQK-------EVEIKDSTLRQQGEKIAQEVIN----RLRKKDNL------KNVPITVALYKQASKTSIVPG----NFIAKTEVKAGSTDISNWDDINEKY-VF--YPADTTTAEKYPDDTEVFK-RFKNSIEEYFPNYTGVVGTALYENDEMKKMKIDIPMQFYG-KSEVVAFTQFL-TGEVMDYYSKSSVDVEVNITSSDGQEAVIIRNAGDKE--PTVHIYD-------------------------------------------------------- 4PXG Chain:A ((26-509)) TKQAVHNRAKEAV----------GKSVLELNGGESIKSSVGDAFENWF---GVALKATPFKKLKNGKYSSKERLVLNIINYEKVANENFETSSFLSKNNTIELAFYEYIKGTPSDNWIIKEAVLYEMHKNPIDYEIIKQDWEIINQYIN-----EGKAHELSEGLTSYLAPCTKGANASSLRNQPYSDIKAKQRAFSLKSGYMTSILRKYVLGDEKIDSIVKDPFEIKEKSIEDIVFEKFQPYINWSIDKLCEHFSINKGEKGLNYRIASAILNLKGKTTKSKPFPEVEEFEKSSIVVKTVHF-NKKNVNKESMSFGAFKFEELANEEWEDSEGYPSAQWRNFLLE-----TRFLFFVVKEDED--GVDIFKGIKFFSMPEEDINGPVKRMWDDTVKKLKEG-VTLEAVPDKSTKDGWRIKNNFVDKSDDLICHVRPHTNNRDYRGGSNADKLPKKINWINRPDSDDYSDEWMTKQSFWINNDYIKKQVEDLL

General information: TITO was launched using: RESULT: Template: 4PXG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1552 -15243 -9.82 -41.31 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -9.82 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.164

(partial model without unconserved sides chains): PDB file : Tito_4PXG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4PXG-query.scw PDB file : Tito_Scwrl_4PXG.pdb: