Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQ-WWHQAF-YNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL 4EA3 Chain:A ((166-397)) ---------------------------------------------------------------------------------NLALADTL-VLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHP----TSSKAQAVNVAI-WALASVVGVP-VAIMGSAQVEDEE------IECLVEIPTPQDYWGPVFAICIFLFS--FIVPVLVISVCYSLMIRRLRGV--------RLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDE

General information: TITO was launched using: RESULT: Template: 4EA3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -182899 for 1546 contacts (-118.3/contact) + 2D Compatibility (PS) -22600 + (NN) -3194 + (LL) 7956 1D Compatibility (HY) -18800 + (ID) 2850 Total energy: -222387.0 ( -143.85 by residue) QMean score : 0.171

(partial model without unconserved sides chains): PDB file : Tito_4EA3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4EA3-query.scw PDB file : Tito_Scwrl_4EA3.pdb: