Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLY-ISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLI----CFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC 4EA3 Chain:A ((132-401)) -------------------------YLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHP-------TSSKAQAVNVAIWALASVVGVPVAIMGSA-QVEDEEIECLVEIPTPQDYWGPVFAICIF--LFSFIVPVLVISVCYSLMIRRLRGVRLLSGSR-EKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVA---ILRFCTA---LGYVNSCLNPILYAFLDENFKACFR-----------------------------

General information: TITO was launched using: RESULT: Template: 4EA3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -254568 for 1920 contacts (-132.6/contact) + 2D Compatibility (PS) -26460 + (NN) -10237 + (LL) 4032 1D Compatibility (HY) -23200 + (ID) 3450 Total energy: -313883.0 ( -163.48 by residue) QMean score : 0.256

(partial model without unconserved sides chains): PDB file : Tito_4EA3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4EA3-query.scw PDB file : Tito_Scwrl_4EA3.pdb: