Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFL---------KQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYH----VMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK 4N6H Chain:A ((128-402)) -------------------------ITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRS------LRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRR---------DPLVVAALHLCI-ALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG-------------------

General information: TITO was launched using: RESULT: Template: 4N6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -223159 for 1993 contacts (-112.0/contact) + 2D Compatibility (PS) -26663 + (NN) -4600 + (LL) 5240 1D Compatibility (HY) -24800 + (ID) 3850 Total energy: -277832.0 ( -139.40 by residue) QMean score : 0.195

(partial model without unconserved sides chains): PDB file : Tito_4N6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N6H-query.scw PDB file : Tito_Scwrl_4N6H.pdb: