Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQPSKTTKLTKDEVDRLISDYQTKQDEQAQETLVRVYTNLVDMLAKKYS-KGKSFHEDLRQVGMIGLLGAIKRYDPVVGKSFEAFAIPTIIGEIKRFLRDKTWSVHVPRRIKELGPRIKMAVDQLTTETQRSPKVEEIAEFLDVSEEEVLETMEMGKSYQALSVDHSIEADSDGSTVTILDIVGSQEDGY------------ERVNQQLM---LQSVLHVLSDREKQIIDL--TYIQNKSQ--KETGDILGISQMHVSRLQRKAVKKLREALIEDPSMELM 1L9Z Chain:H ((192-424)) -----------------------AREGEAARQHLIEANLRLVVSIAKKYTGRGLSFL-DLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEA-------------MGPGWDAKRVEETLKIAQE--PVSLETPI-------DFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLK------------

General information: TITO was launched using: RESULT: Template: 1L9Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain H - contact count / total energy / energy per contact / energy per residue : 542 -54251 -100.09 -265.94 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain H : 0.72 3D Compatibility (PKB) : -100.09 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.72 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_1L9Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L9Z-query.scw PDB file : Tito_Scwrl_1L9Z.pdb: