Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRGFFGKAIFVVLAVFIMMPLLGIEAVRASELQQHVYDRAHLLSKAEIGKLESLSAKLGAKRDTDFIIITTKSTN-GEDIADYTGDFYDRYG-----K-GSTAILTIDMTNREVFIAGFKKAEQYLDNSRLNSIRNT-ISSD----LSNENYFEAFETYIQLSYKDMGIKPGVNPDNIFFTWWFQLIAAIAVGGIAVSIMLYHAGGKVTVNGSTYMDQRTSDVIDQYDTYIRTTVTRERKPSDKDSGSDGGVTKGGTSYSGSRGSF 3PVH Chain:A ((9-147)) --------------------------NDGPPKETYVVDDAGVLSRVTKSDLKKLLSDLEYRKKLRLNFITVRKLTSKADAFEYADQVLEKWYPSIEEGNNKGIVVLITS-QKEGAITGGP----AFIEAVGENILDATVSENLPVLATDEKYNEAVYSSAKRLVAAIDGQ------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3PVH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 591 -56044 -94.83 -441.29 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -94.83 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_3PVH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PVH-query.scw PDB file : Tito_Scwrl_3PVH.pdb: