Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVTYWTGENLTLRAIQPEDIVIFDSLDDEILRNMDSLHFPR---SANNMREWVEEQLEKD-EFRFIAVESDNNIVGMIETFDCDRKNGTFGYYLAVFEPYRGKGFAKEMILMVLRFFFLELAYQKVNTTVYSFNNPSIRLHEKLGFMKEGQLRKIIFTKGAYYDGICFGMTREEFELNHG 4R57 Chain:A ((8-160)) ----------LTLRALERGDLRFIHNLNNN--RNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQD----------------

General information: TITO was launched using: RESULT: Template: 4R57.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 551 -11495 -20.86 -77.14 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -20.86 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.565

(partial model without unconserved sides chains): PDB file : Tito_4R57.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R57-query.scw PDB file : Tito_Scwrl_4R57.pdb: