Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCF---EPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMII-----LTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV 4EA3 Chain:A ((131-405)) ----------------------------LYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTD-ILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHP-------TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFS----FIVPVLVISVCYSLMIRRLRGVRLLSGSREKD-RNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRF------CTALGYVNSCLNPILYAFLDENFK---ACFR---------------------------

General information: TITO was launched using: RESULT: Template: 4EA3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -236330 for 1957 contacts (-120.8/contact) + 2D Compatibility (PS) -26001 + (NN) 1340 + (LL) 5396 1D Compatibility (HY) -24000 + (ID) 4150 Total energy: -283745.0 ( -144.99 by residue) QMean score : 0.249

(partial model without unconserved sides chains): PDB file : Tito_4EA3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4EA3-query.scw PDB file : Tito_Scwrl_4EA3.pdb: