Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVSLNHPASNTTSTKNNNSAFFYFESCQPPSPALLLLCIAYTVVLIVGLFGNLSLIIIIFKKQRKAQNFTSILIANLSLSDTLVCVMCIHFTIIYTLMDHWIFGDTMCRLTSYVQSVSISVSIFSLVFTAVERYQLIVNP-RGWKPSVTHAYWGITLIWLFSLLLSIPFFLSYHLTDEPFRNLSLPTDLYTHQVACVENWPSKKDRLLFTTSLFLLQYFVPLGFILICYLKIVICLRRRNAKVDKKKENEGRLNENKRINTMLISIVVTFGACWLPRISSMSSLTGIMRC 1F88 Chain:A ((42-267)) ----------------------------------------AYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPH--------EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAA-------SATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS

General information: TITO was launched using: RESULT: Template: 1F88.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -180818 for 1642 contacts (-110.1/contact) + 2D Compatibility (PS) -21681 + (NN) 2072 + (LL) 3080 1D Compatibility (HY) -26400 + (ID) 2650 Total energy: -226397.0 ( -137.88 by residue) QMean score : 0.284

(partial model without unconserved sides chains): PDB file : Tito_1F88.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1F88-query.scw PDB file : Tito_Scwrl_1F88.pdb: