Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNREMLYLNRSDIEQAGGNHSQVYVDALTEAL---TAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIKRVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIM---------DVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 2I99 Chain:A ((1-306)) -SRVPAFLSAAEVEEHL-RSSSLLIPPLETALANFSSGPEGGVMQPVRTVVPVTKHRGYLG----VMPAYSAAEDALT-TKLVTFYEDRGITSVVPSHQATVLLFEPSNGTLLAVMDGNVITAKRTAAVSAIATKFLKPPSSEVLCILGAGVQAYSHYEIFTEQFS-FKEVRIWNRTKENAEKFADTVQGE-----VRVCSSVQEAVAGADVIITVTLATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKEAVLYVD-------SQEAALKESGDVL-----LSGAEIFAELGEVIKGVKPAH--CEKTTVFKSLGMAVEDTVAAKLIY---------------

General information: TITO was launched using: RESULT: Template: 2I99.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -141754 for 2587 contacts (-54.8/contact) + 2D Compatibility (PS) -31542 + (NN) -14673 + (LL) 2728 1D Compatibility (HY) -17600 + (ID) 3950 Total energy: -206791.0 ( -79.93 by residue) QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_2I99.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I99-query.scw PDB file : Tito_Scwrl_2I99.pdb: