Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMQQLSLKHRLNNGDSVYGIFNSIPDPLMIEVIAASGYDFVVIDTEHVAINDETLAHLIRAAEAAHIIPIVRVTAVIDRDIIKVLDMGARGIIVPHVKDRETVEHIVKLSRYYPQGLRSLNG--GRMARFGRTPLLDAMEMANEHIMVIAMIEDVEGVMAIDDIAQVEGLDMIVEGAADLSQSLGIPWQTRDDQVTSHVQHIFEV----VNAHGKH--FCAL-PREDEDIAKWQAQ----GVQTFILGDDRGKIYRHLSASLATSKQKGDDG 2VWT Chain:A ((9-245)) ------FKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGR--IENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYP----DNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSD-----------------------

General information: TITO was launched using: RESULT: Template: 2VWT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -160577 for 1747 contacts (-91.9/contact) + 2D Compatibility (PS) -23851 + (NN) -5274 + (LL) 1860 1D Compatibility (HY) -13600 + (ID) 3850 Total energy: -205292.0 ( -117.51 by residue) QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_2VWT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VWT-query.scw PDB file : Tito_Scwrl_2VWT.pdb: