Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQEKAVIRDPKKLNAFDLRWIASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLTYLGHRALAYFIGSKDKEDITMVVRSHFGAQWGFLITLLYFLAIYPICLAYGVGITNVFDHFFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICNALVYPLCLILLLFSLYLIPYWQGANLFVVPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVGKEYGAFKEYKLNQIELGTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKE---GLEGIIIQSLKLKQASKTLSVGVTIFLWLTITLVAYINPNILDFIENLGGPIIALILFVMPMIAFYSVSSLKRFRNFKVDIFVFVFGSLTALSVFLGLF 4A5W Chain:A ((1162-1220)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIYKRIV

General information: TITO was launched using: RESULT: Template: 4A5W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -7619 for 249 contacts (-30.6/contact) + 2D Compatibility (PS) -5814 + (NN) -950 + (LL) 25100 1D Compatibility (HY) -4400 + (ID) 850 Total energy: 5467.0 ( 21.96 by residue) QMean score : 0.041

(partial model without unconserved sides chains): PDB file : Tito_4A5W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4A5W-query.scw PDB file : Tito_Scwrl_4A5W.pdb: