Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEDRLSAEDKKFLEVERALKEAALNPLRHATEELFGDFLKMENITEICYNGDKVVWVLKNNGEWQPFDVRNKKAFSLSRLMHFARCCASFKKKTIDNYENPILSSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKTTYIKSIMEFIPKEERIISIEDTEEIVFKHHKNYTQLFF----GGNITSADCLKSCLRMRPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLANMSSSNSAARNIKFESLIEGFKDLIDMIVHINHHKQCDEFYIKHR 4IHQ Chain:A ((192-372)) -----------------------------------------------------------------------------------------------------PVVDASLPDGSRVNFVYG-VDISRRGSNLTVRKFSRV--PTSITQLIMFGTLSSMMAAYIWTMLDE---GMNLFVCGETASGKTTTLNAITAFIPPNLKIVTIEDTPELTVPHSNWVAEVTRETGGEGTIKLFDLLKAALRQRPNYILVGAIRDKEGNVAFQAMQTGH-SVMATFHAANITTLIQRLTGYPIEVPKSYINNLNIALFQTALYDKKGNLIRRVVEVDEIIDIDP

General information: TITO was launched using: RESULT: Template: 4IHQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -51109 for 1250 contacts (-40.9/contact) + 2D Compatibility (PS) -19104 + (NN) -6092 + (LL) 8176 1D Compatibility (HY) -11200 + (ID) 2850 Total energy: -82179.0 ( -65.74 by residue) QMean score : 0.366

(partial model without unconserved sides chains): PDB file : Tito_4IHQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IHQ-query.scw PDB file : Tito_Scwrl_4IHQ.pdb: