Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LDIQESVIGIDLGGTKILIGEVTKDGEVLNSKSYPSNTENQTKATETLLKVLADYTQNIGFIAPKQTGIGVGLVGRVDHKSGVWLEIEPG----KSNPTPLAGILEAKTGLPVSLGNDVVCATMAEKQFGWGRETNDFIYLNVGTGLAAGFVVDGRITQGGHFNAGEVGHAVVDIHSDVLCGCGRRGCVERLASGLGIKEEALRHLNSYPTSILAETQTELTGKMVLHAAEQKDELAEKIIDNATFQLANLIMNLVRTTDPECVILGGGVTRNEHFFQKIQDNLQSNTIRFVTKGVVRSKLEKDKVGLIGAAVIGMRLGNEGGKE 4HTL Chain:A ((6-285)) ------IAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKVFLAENTD--------VTGIAVSAPGYVNPKTGL---ITMGGAIRRFDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQDLDDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSE----------RPGAFRPGKYTLNETTTMLVLRRQY-AELTGRPLEEITGEEIFANYDAHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFIGGGITSRPTFIAELKHHMESFGLR---DTIIETATHKNQAGLLGA--------------

General information: TITO was launched using: RESULT: Template: 4HTL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -111878 for 2232 contacts (-50.1/contact) + 2D Compatibility (PS) -29725 + (NN) -17011 + (LL) 2336 1D Compatibility (HY) -17200 + (ID) 4150 Total energy: -177628.0 ( -79.58 by residue) QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_4HTL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HTL-query.scw PDB file : Tito_Scwrl_4HTL.pdb: