Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNA----VRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEE---KWIDKMEQLSVAALLGEAIVRVHENASVSSLFE 2HCR Chain:A ((3-313)) --------NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWR---NCTIVSPDAGGAKRVTSIADRLNVDFALIHKER------DRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTI--PQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLF-

General information: TITO was launched using: RESULT: Template: 2HCR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -279553 for 2517 contacts (-111.1/contact) + 2D Compatibility (PS) -33524 + (NN) -24114 + (LL) 640 1D Compatibility (HY) -30800 + (ID) 7300 Total energy: -374651.0 ( -148.85 by residue) QMean score : 0.624

(partial model without unconserved sides chains): PDB file : Tito_2HCR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HCR-query.scw PDB file : Tito_Scwrl_2HCR.pdb: