Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MEKNIDVLQNWLKDQGAEVGFLTDPENIAYFSGYH-SEPHERVLGLAVFSDSEPFLFTPALEVEDVRGGDWTHPAYGYNDTENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLFSGSSFI--PIEHKIEQIRLIKTEAELKILKEAALLADYAVQVGVDEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVAFGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGFGDYFPHRLGHGLGASVHEFPSITETNSMELQENMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVIE |
| 2HOW Chain:A ((10-356)) | -----------LGERGFDGALISPGTNLYYLTGLRLHEVGERLAILAVSAEGDYRFLAPSL-YENVVN---NFPATFWHDGENPYAKLREILEELGISKGRILIE----DTMRADWLIGIMKLGKFTFQPLSSLIKELRMIKDKEEVKMMEHASRIADKVFEEILTWDLIGMKERELALKIELLIRELS-DGIAFEPIVASGENAANPHHEPGERKIRKGDIIILDYGARWKGYCSDITRTIGLGELDERLVKIYEVVKDAQESAFKAVREGIKAKDVDSRAREVISKAGYGEYFIHRTGHGLGLDVHEEPYIGPDGEVILKNGMTFTIEPGIYVPGLGGVRIEDDIVVDEGKGRRLTKAERELIIL- |
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General information:
TITO was launched using:
| RESULT:
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Template: 2HOW.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -130285 for 2927 contacts (-44.5/contact) +
2D Compatibility (PS) -38041 + (NN) -19267 + (LL) 1676
1D Compatibility (HY) -24400 + (ID) 6400
Total energy: -216717.0 ( -74.04 by residue)
QMean score : 0.468
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