Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEQKDMYVLGIETSCDETAAAIVKNGKEIISNVVASQIESHKRFGGVVPEIASRHHVEQITLVIEEAFRKAGMTYSDIDAIAVTEGPGLVGALLIGVNAAKALSFAYNIPLVGVHHIAGHIYANRL--VEDIVFPALALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGLPYPGGPQIDKLAEKGNDNIPLPRAWLEEGSYNFSFSGLKSAVINTLHNASQKGQEIAPEDLSASFQNSVIDVLVTKTARAAKEYDVKQVLLAGGVAANRGLRAALEKEFAQHEGITLVIPPLALCTDNAAMIAAAGTIAFEKGIRGAYDMNGQPGLELTSYQSLTR 2IVP Chain:A ((1-302)) ------MLALGIEGTAHTLGIGIVSEDK-VLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGVKDPV----GLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYIELPYAV---KGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREML-RIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGI----------------------

General information: TITO was launched using: RESULT: Template: 2IVP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1818 -229461 -126.22 -764.87 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -126.22 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.621

(partial model without unconserved sides chains): PDB file : Tito_2IVP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IVP-query.scw PDB file : Tito_Scwrl_2IVP.pdb: