Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVNKESLVADELHRMFLAGELQITVEEDINNISERL---RNGDLSLDRLSGEDVFIKETVNEALRRVEQ 2OBH Chain:A ((98-137)) ---------FKNLKRVAKELGENLT-DEELQEMIDEADRDGDGEVSEQEF--------------------

General information: TITO was launched using: RESULT: Template: 2OBH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 69 -7701 -111.60 -208.12 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -111.60 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.621

(partial model without unconserved sides chains): PDB file : Tito_2OBH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OBH-query.scw PDB file : Tito_Scwrl_2OBH.pdb: