Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFEWNKYFPFHNQFSKEALKKADPKEVETYVNRVMESVFGSDYAAQFPFRDPLPQKEHPAKPDAKPDVKPDIDIFETADHVFVKVPISEEW--LEQVRIKHTSHELWLENLPRADHPKKVNLPCLVKRKGTKAVYKDGLLEVMFQKQQDYNMSEVEIIR 1Z9A Chain:A ((87-173)) ----------------------DPKNVETALNKTLADL-KVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCG----DGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGA---------------------------------------------

General information: TITO was launched using: RESULT: Template: 1Z9A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 257 1786 6.95 21.01 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 6.95 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_1Z9A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Z9A-query.scw PDB file : Tito_Scwrl_1Z9A.pdb: