Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNKIYDWVDERLDITPMWRDIADHEVPEHVNPAHHFSAFVYCFGGLTFFVTVIQVLSGMFLTMYYVPDIKNAWESVYYLQNEVAFGQIVRGMHHWGASLVIVMMFLHTLRVFFQGAYKKPRELNWIVGVLIFFVMLGLGFTGYLLPWDMKALFATKVGLQIAEATPLIGTQVKTLLAGHPDIVGAQTLTRFFAIHVFFLPAALFGLMAAHFIMIRKQGISGPL 4I7Z Chain:A ((3-215)) ---NVYDWFQERLEIQALADDVTSKYVPPHVN-------IFYCLGGITLTCFLIQFATGFAMTFYYKPTVTEAYASVQYIMNEVSFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWISGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSS-VGQATLTRYYSAHTFVLPWLIAVFMLLHFLMIRKQGISGPL

General information: TITO was launched using: RESULT: Template: 4I7Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 689 -116839 -169.58 -548.54 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -169.58 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_4I7Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I7Z-query.scw PDB file : Tito_Scwrl_4I7Z.pdb: