Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLTFYSYPSCTSCRKTKHWLKAHQIEFNERHLFRETPTREELKYILS-LTTEGIDEILATRSQTFKNLNLNIEEMTVNEVLELLIEKPKLLRRPILVDNKKLVIGYNPGELLKLSKKKTVHQSA 3RDW Chain:A ((7-120)) ----VTIYHNPRCSKSRETLALVEQQGITPQVVLYLETPPSVDKLKELLQQLGFSDARQLMRTKEDLYKTLNLDDRGLTQDQLLQAMADNPKLIERPIVVTQGKARIGRPPEQVLEIL---------

General information: TITO was launched using: RESULT: Template: 3RDW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 501 -23967 -47.84 -212.09 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -47.84 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.630

(partial model without unconserved sides chains): PDB file : Tito_3RDW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RDW-query.scw PDB file : Tito_Scwrl_3RDW.pdb: