Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKITFIGAGSTIFAKNVLGDCLLTEALNGFEFALY--DIDPKRLQESQLMLENLRDRYNPSVAINSYDDRKLALQNAGYVINAI--------QVGGYKPSTVIDFEIPKRYGL-----RQTIADTVGIGGIFRSLRTIPVLFDIAKDMEEMCPDAWFLNYTNPMATLTGAMLRYTNIKTIGLCHSVQVCTKDLFKALGMEHDGIEERIAGINHMAWLLEVKKDGTDLYPEI-----KRRAKEKQKTKHHDMVRFELMDKFGYY----VTESSEHNA-EYH-------PYFIKRNYPELISELQIP-LDEYPRRCVKQIENWEKMRDDIVNN--KNLTHER---------SKEYGSRIIEAMETNEPFTFGGNVLNTGLITNLPSKAVVEVT-----CVADRKKITPCFAGELPEQLAALNRTNINTQLMTIEAAVTRKKEAVYQAAMLDPHTSAELSMKDIISMCDDLFAAHGDWLPEYK 1VJT Chain:A ((14-467)) --KISIIGAGSVRFALQLVGDIAQTEELSREDTHIYMMDVHERRLNASYILARKYVEELNSPVKIVKTSSLDEAIDGADFIINTAYPYDPRYHDSGSQRWDEVT--KVGEKHGYYRGIDSQELNMVSTYTYVLSSYPDMKLALEIAEKMKKMAPKAYLMQTANPVFEITQAVRRWTGANIVGFCHGV-AGVYEVFEKLDLDPEEVDWQVAGVNHGIWLNRFRYRGEDAYPLLDEWIEKKLPEWEPKNPWDTQMSPAAMDMYKFYGMLPIGDTVRNGSWKYHYNLETKKKWFGK--FGGIDNEVERPKFHEQLRRARERL---IKLAEEVQQNPGMKLTEEHPEIFPKGKLSGEQHIPFINAIANNKRVRLFLNVENQGTLKDFPDDVVMELPVWVDCCGIHREKVEPDLTHRI--KIFYL-WPRILRMEWNLEAYISRDRKVLEEILIRDPRTK---SYEQIVQVLDEIF-----------

General information: TITO was launched using: RESULT: Template: 1VJT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2189 56047 25.60 138.39 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 25.60 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.423

(partial model without unconserved sides chains): PDB file : Tito_1VJT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VJT-query.scw PDB file : Tito_Scwrl_1VJT.pdb: