Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQATFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRGGDVRFAKTSRMLSDLAGGHADRSWGQRIRE----YTKPLVLILDDFAM---REHTAMHADDLYELISDRAITGKPLILTSNRAPNNWYGL-------FPNPVVAESLLDRLINTSHQILMDGPSYRPRKRPGRTTS 1L8Q Chain:A ((40-169)) -------------------------------------------------------------------------------------------------------IFIYGSVGTGKTHLLQAAGNEAKKRGYRVIYSSA----DDFAQAMVEHLKKGTINEFRNMYKSVDLLLLDDVQFLSGKERTQI---EFFHIFNTLYLLEKQIILASDRHPQKLDGVSDRLVSRFEGGILVEIELD---------------------------

General information: TITO was launched using: RESULT: Template: 1L8Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -60985 for 785 contacts (-77.7/contact) + 2D Compatibility (PS) -12347 + (NN) -4942 + (LL) 9504 1D Compatibility (HY) -9200 + (ID) 1700 Total energy: -79670.0 ( -101.49 by residue) QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_1L8Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L8Q-query.scw PDB file : Tito_Scwrl_1L8Q.pdb: