Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRWLGVALGCSGLAIALACAGVLLAPADMAASSSSPSPARTVAALPAVDDRPPPPAPVRSQAAAPAYEAEPPVA--------ELDREQAIQFMQMLRDEGDPRSPPLGGLQPRQGATAQELADPKQYQAFEERQTRELVQAYTSGVQQIPEIRARIEAAEQGGERSAEEIDEARAALGQLEMMRDKLQRESPQLLPGDSAPTSPAAP 4O4R Chain:A ((4-81)) -------------------------------------RPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDK

General information: TITO was launched using: RESULT: Template: 4O4R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 1249 for 259 contacts (4.8/contact) + 2D Compatibility (PS) -7592 + (NN) -12455 + (LL) 2604 1D Compatibility (HY) 800 + (ID) 1100 Total energy: -16494.0 ( -63.68 by residue) QMean score : 0.386

(partial model without unconserved sides chains): PDB file : Tito_4O4R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O4R-query.scw PDB file : Tito_Scwrl_4O4R.pdb: