Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEA-AATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDER--RVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG---VLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG 4MX9 Chain:A ((29-288)) -----------YKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFE-DKGYYYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDK-IGTAYYIAPEVLHG-TYD-EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKE

General information: TITO was launched using: RESULT: Template: 4MX9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -128961 for 1927 contacts (-66.9/contact) + 2D Compatibility (PS) -27515 + (NN) -16400 + (LL) 776 1D Compatibility (HY) -22400 + (ID) 4150 Total energy: -198650.0 ( -103.09 by residue) QMean score : 0.439

(partial model without unconserved sides chains): PDB file : Tito_4MX9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MX9-query.scw PDB file : Tito_Scwrl_4MX9.pdb: