Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGRSAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQI--MADTGLAYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCNAM-SRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR 4ICN Chain:B ((12-297)) ---------------IVALITPLNSDGTVDYTSLEKLVEYHITEGTDAIVAVGTTGESATLPISEHIAVVGQTVKFASGRIPVIGGNGANATAEAIELTKAQNKLGVAAMLGVTPYYNKPSPKGLIAHYTAVAASTDIPQILYNVPGRTAVDMLPETIAQLVEVPNIIGVKDATGDVARVKQLRDLCGNDFLLYSGDDATAREFLTLGGDGVISVANNIVPKLFKLMCDAALAGDTQAAMAAEDQIKGLFSALFCEANPIPVKWAAHKMGLISQGDIRLPLTELSTEFHGLLLDAMKNARI--

General information: TITO was launched using: RESULT: Template: 4ICN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -166264 for 2491 contacts (-66.7/contact) + 2D Compatibility (PS) -31317 + (NN) -22957 + (LL) 1476 1D Compatibility (HY) -17600 + (ID) 4950 Total energy: -241612.0 ( -96.99 by residue) QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_4ICN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ICN-query.scw PDB file : Tito_Scwrl_4ICN.pdb: