Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKQVYIIHGYRASSTNHWFP-WLKKRLLADGVQADILNMPNPLQPR-----------LEDWLDTLSLYQHTLH-ENTYLVAHSLGCPAILRFLEHLQLRKQLGGIILVSGFAKSLPTLQMLDEFTQGSFDHQKIIESAKHRAVIASKDDQIVPFSFSKDLAQQID-AALYEVQHGGHFLEDEGFTSLPIVYDVLTSYFSKETR 3BDI Chain:A ((27-206)) -RRSIALFHGYSFTS-MDWDKADLFNNYSKIGYNVYAPDYPGFGRSASSEKYGIDRGDLKHAAEFIRDYLKANGVARSVIMGASMGGGMVIMTTLQY--PDIVDGIIAVAPAWVESLK--------------GDMKKIRQKTLLVWGSKDHVVPIALSKEYASIISGSRLEIVEGSGHPVYIE---KPEEFVRITVDFLRN---

General information: TITO was launched using: RESULT: Template: 3BDI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 925 -134000 -144.86 -807.23 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -144.86 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_3BDI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BDI-query.scw PDB file : Tito_Scwrl_3BDI.pdb: