Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 2VTS Chain:A ((4-287)) -----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-----------PSTAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP

General information: TITO was launched using: RESULT: Template: 2VTS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -188163 for 2089 contacts (-90.1/contact) + 2D Compatibility (PS) -28427 + (NN) -16726 + (LL) 712 1D Compatibility (HY) -30800 + (ID) 6600 Total energy: -270004.0 ( -129.25 by residue) QMean score : 0.532

(partial model without unconserved sides chains): PDB file : Tito_2VTS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VTS-query.scw PDB file : Tito_Scwrl_2VTS.pdb: