Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTG--TYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVRQSKRPTGSNATITFSNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW 1TE1 Chain:B ((15-189)) --------------------------------YYSFWTNGGGEVTYTNGDNGEYSVTWVDCGDFTSGKGWNPANA-QTVTY-SGEFNPSGNAYLAVYGWTTDPLVEYYILESYGTYNPSSGLTSLGQVTSDGGTYDIYSTQRVNQPSIEG-TSTFNQYWSVRTEKRVGG---TVTTANHFAAWKALGLEMGT-YNYMIVSTEGYESSGSSTITV-

General information: TITO was launched using: RESULT: Template: 1TE1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 984 -16632 -16.90 -96.14 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -16.90 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_1TE1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TE1-query.scw PDB file : Tito_Scwrl_1TE1.pdb: