Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQA----YPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLH--NMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLA-ELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFLSSPLSSAINGAALRADGGLVRSVF 3QRW Chain:A ((27-278)) -------EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEA--DGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRLGGGATAELADELWLDVVETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELAR-TGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITAR----VPIGRYVQPSEVAEMVAYLIGPGAAAVTAQALNVCGGL-----

General information: TITO was launched using: RESULT: Template: 3QRW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1333 -70086 -52.58 -286.07 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -52.58 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_3QRW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QRW-query.scw PDB file : Tito_Scwrl_3QRW.pdb: