Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDGNRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQRDPDELAALIEIITDVVEEI-C-APANHWSVRTVGDLGLIGEEPARRLRGAVESTPEVASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDAVTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHWPAFRHVDFLRALRDYSARHRSYGR 4H8E Chain:A ((20-252)) --------------------------DSSNIPEHIAIIMDGNGRWAKKRKMP-RIKGHYEGMQTIKKITRIASDIGVKYLTLYAFSTENWSRPESEVNYIMNLPVNFLKTFLPELIEKNVKVETIGFTDKLPKSTIEAINNAKEKTANNTGLKLIFAINYGGRAELVHSIKNMFDELHQ----QGLNSDIIDETYINNHLMTKDYPDPELLIRTSGEQRISNFLIWQVSYSEFIFNQKLWPDFDEDELIKCIKIYQSRQRRFGG

General information: TITO was launched using: RESULT: Template: 4H8E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -125031 for 1795 contacts (-69.7/contact) + 2D Compatibility (PS) -24873 + (NN) -6979 + (LL) 2316 1D Compatibility (HY) -17200 + (ID) 3450 Total energy: -175217.0 ( -97.61 by residue) QMean score : 0.604

(partial model without unconserved sides chains): PDB file : Tito_4H8E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H8E-query.scw PDB file : Tito_Scwrl_4H8E.pdb: