Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVSSASLAGKVAFVQGGSRGIGAAIVRRLAAEGASVAFTYVSSADKSRALAAELEGAGASILALHADSADAAALVAAVDEAAARFGRIDILVNNAAVLALGSVEELPLADFERTLAINVRSVFVATQAAV---KHMGDGGRVISIGSTNAERMPFAGGATYAMSKSALVGLTKGLARDLGPRGITVNNVQPGPVDTDM----------NPDDGDFAEALKGLMALPRYARSEEIASFVAYLAGPEAAYITGASLTIDGGFSA 3WYE Chain:B ((3-252)) ----------KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDA-TAKAVASEINQAGGHAVAVKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAVEAFKKEGHGGKIINAASIAAIQ-GFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCPGIVGTGMWEQIDAELSK-------------SIALGRPSVPEDVAGLVSFLASPDSDYMTGQSLLIDGGMVF

General information: TITO was launched using: RESULT: Template: 3WYE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -122420 for 1943 contacts (-63.0/contact) + 2D Compatibility (PS) -24656 + (NN) -14900 + (LL) 684 1D Compatibility (HY) -17600 + (ID) 4600 Total energy: -183492.0 ( -94.44 by residue) QMean score : 0.661

(partial model without unconserved sides chains): PDB file : Tito_3WYE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WYE-query.scw PDB file : Tito_Scwrl_3WYE.pdb: