Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 2VTR Chain:A ((4-287)) -----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-----------PSTAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP

General information: TITO was launched using: RESULT: Template: 2VTR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -186101 for 2149 contacts (-86.6/contact) + 2D Compatibility (PS) -29123 + (NN) -17424 + (LL) -52 1D Compatibility (HY) -32000 + (ID) 6650 Total energy: -271350.0 ( -126.27 by residue) QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_2VTR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VTR-query.scw PDB file : Tito_Scwrl_2VTR.pdb: