Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERD------QEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP 4BL1 Chain:A ((3-264)) ----------------------KDYDELLKYYELHETIGTGGFAKVKLACHILTGEM-VAIKIMDKN-TL-------LPRIKTEIEALKNLR----HQHICQLYHVLETANKIFMVLEY-CPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHK-LKLIDFGLCA----K-------SLAYAAPELIQGK---GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI-------------------------

General information: TITO was launched using: RESULT: Template: 4BL1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -168469 for 1831 contacts (-92.0/contact) + 2D Compatibility (PS) -24225 + (NN) -9211 + (LL) -436 1D Compatibility (HY) -27200 + (ID) 4450 Total energy: -233991.0 ( -127.79 by residue) QMean score : 0.445

(partial model without unconserved sides chains): PDB file : Tito_4BL1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BL1-query.scw PDB file : Tito_Scwrl_4BL1.pdb: