Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENK----LAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRN-----KIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGDDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGF-RVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAG----TLSGNPLAMTSGYETLSQLTPETY-EYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK 2E54 Chain:A ((11-343)) ---------------------------------PATFV-YGKGSWIYDEKGNAYLDFTSGIAVNVLGHSHPRLVEAIKDQAEK--LIHCSNLFWNRPQMELAEL-LSKNTFGGKVFFANTGTEANEAAIKIARKYGKKKSEKKYRILSAHNSFHGRT------LGSLTAT-GQPKYQKPFEPLVPGFEYFEFNNVEDLR---RKMSEDVCAVFLEPIQGESGIVPATKEFLEEARKLCDEYDALLVFDEVQCGMGRTGKLFAYQKYGVVPDVLTTAKGLGGGVPIGAV-----IVNERA---NVLEPGDHGTTFGGNPLACRAGVTVIKELTKEGFLEEVEEKGNYLMKKLQEMKEEYDVVADVRGMGLMIGIQFRE-EVSNREVATKC------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2E54.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -147199 for 2616 contacts (-56.3/contact) + 2D Compatibility (PS) -34896 + (NN) -19168 + (LL) 7484 1D Compatibility (HY) -18800 + (ID) 5600 Total energy: -218179.0 ( -83.40 by residue) QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_2E54.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2E54-query.scw PDB file : Tito_Scwrl_2E54.pdb: