Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDK-MGGPEEFIQRF-LPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVL--QGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSF----PTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 2CN5 Chain:A ((14-284)) -----LRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKR-----------NVETEIEILKKLNHPCIIKIKNFFDAEDYYI--VLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGET--SLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDE

General information: TITO was launched using: RESULT: Template: 2CN5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131835 for 1803 contacts (-73.1/contact) + 2D Compatibility (PS) -26250 + (NN) -11116 + (LL) 1540 1D Compatibility (HY) -20400 + (ID) 4850 Total energy: -192911.0 ( -106.99 by residue) QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_2CN5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CN5-query.scw PDB file : Tito_Scwrl_2CN5.pdb: