Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMD--TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTID-AGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD 4O27 Chain:B ((13-272)) ---------------------------------------------------------KIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITV-LSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ------IATILREILKGLDYLHSE-KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNEFVGTPFWMAPEVI----KQSAYDSKADIWSLGITAIELARGEPPHSEL-HPMKVLFLIPKNNPPTLEGN-YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRW

General information: TITO was launched using: RESULT: Template: 4O27.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -121786 for 2077 contacts (-58.6/contact) + 2D Compatibility (PS) -26882 + (NN) -10631 + (LL) 2732 1D Compatibility (HY) -16400 + (ID) 4250 Total energy: -177217.0 ( -85.32 by residue) QMean score : 0.381

(partial model without unconserved sides chains): PDB file : Tito_4O27.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O27-query.scw PDB file : Tito_Scwrl_4O27.pdb: