Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNVAIVGDGGHGKVIRELINARSDTRLAAVLDDKFKTFEGGKEWYTGPPKAVTELRRLIP--DVLFLIAVGNNSVRKQLAERLGL-GKDDFITLIHPSAIVSKSAVIGEGTVIMAGAIIQADARIGAHCIINTGAVAEHDNQISDYVHLSPRATLSGAVSVQEGAHVGTGASVIPQIIIGAWSIVGAGSAVIRSIPDRVTAAGAPARIISSIQTSNKG 4M98 Chain:A ((199-403)) NRKLAVIGAGGHGKVVAELAAALGTYGEIVFLDDRTQGSVNGFPVIGTTLL----LENSLSPEQFDITVAVGNNRIRRQITENA-AALGFKLPVLIHPDATVSPSAIIGQGSVVMAKAVVQAGSVLKDGVIVNTAATVDHDCLLDAFVHISPGAHLSGNTRIGEESRIGTGACSRQQTTVGSGVTAGAGAVIVCDIPDGMTVAGNPAKPL---------

General information: TITO was launched using: RESULT: Template: 4M98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1268 -57597 -45.42 -285.13 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -45.42 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.555

(partial model without unconserved sides chains): PDB file : Tito_4M98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M98-query.scw PDB file : Tito_Scwrl_4M98.pdb: