Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDYQETLYQGYGQRFSIDNMLHEVRTEHQHLVIFENARMGRVMALDGVIQTTEADEFIYHEMLTHVPILAHGAARRVLIIGGGDGGMLREVAKHKSVERITMVEIDGTVVDMCKEFL------------PNHSQGAFDDPRLNLVIDDGMRFVATTEERFDVIISDSTDPIGPGEVLFSENFYQACRRCLNEGGILVTQNGTPFMQLEEVRTTAARTDGLFADWHFYQAAVPTY---------IGGAMTFAWGSTHEGLRRLPLETLRQRFRDSGIATRYYNADIHLGAFALPQYVLQAIGKQDND 2E5W Chain:C ((12-280)) ---------RGYGVAFKVKRKILEEQSEYQKIEVYETEGFGKLLAIDGTVQLVTEGEKSYHEPLVHPAMLAHPNPRRVLIIGGGDGGAIREVLKHEEVEEVIMVEIDKKVIEISAKYIGIDGGILEKMLSDKHEKG-------KLIIGDGVKFIEEN-SGFDVIIVDSTDPVGPAEMLFSEEFYKNAYRALNDPGIYVTQAGSVYLFTDEFLTAYRKMRKVFDKVYYYSFPVIGYASPWAFLVGVKGSIDFMKVDAEKG-KKLGLE--------------YYDPDKHETLFQMPRYIVQML------

General information: TITO was launched using: RESULT: Template: 2E5W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -148327 for 2045 contacts (-72.5/contact) + 2D Compatibility (PS) -26172 + (NN) -8292 + (LL) 2064 1D Compatibility (HY) -23600 + (ID) 5100 Total energy: -209427.0 ( -102.41 by residue) QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_2E5W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2E5W-query.scw PDB file : Tito_Scwrl_2E5W.pdb: