Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKQVYIIHGYRASSTNHWFPWLKK-----RLLADGVQADILNMPNPLQP-----------RLEDWLDTLSLYQHTLH-ENTYLVAHSLGCPAILRFLEHLQLRKQLGGIILVSGFAKSLPTLQ----------------MLDEF---------------T----QG------------SF----DH----QKIIESAKHRAVIASKDDQIVPFSFSKDLAQQID--AALYEVQHGGHFLEDEGFTSLPIVYDVLTSYFSKETR 2QMQ Chain:A ((35-285)) -RPAIFTYHDVGLNYKSCFQP-LFRFGDMQEII-QNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNH--PDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPDMILGHLFSQEELSGNSELIQKYRGIIQHAPNLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAV-VECNSKLDPTQTSFLKMADSGGQPQLT---QPGKLTEAFKYFLQ----

General information: TITO was launched using: RESULT: Template: 2QMQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 929 -136709 -147.16 -772.36 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -147.16 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_2QMQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QMQ-query.scw PDB file : Tito_Scwrl_2QMQ.pdb: