Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence AHNIVLYTGAKMPILGLGTWKSPP-GKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACALVSCASHRDYPFHEEF 4F40 Chain:A ((11-280)) -AMVTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRAS---G-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKD----ILSK--------EGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCT--VTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLG------------KLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRYG-----------------

General information: TITO was launched using: RESULT: Template: 4F40.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -186186 for 2307 contacts (-80.7/contact) + 2D Compatibility (PS) -28594 + (NN) -11848 + (LL) 1628 1D Compatibility (HY) -22000 + (ID) 6200 Total energy: -253200.0 ( -109.75 by residue) QMean score : 0.609

(partial model without unconserved sides chains): PDB file : Tito_4F40.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F40-query.scw PDB file : Tito_Scwrl_4F40.pdb: