Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2CGW Chain:A ((9-264)) ------------------------WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKR----PEN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKK-----------------------------

General information: TITO was launched using: RESULT: Template: 2CGW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -136214 for 1932 contacts (-70.5/contact) + 2D Compatibility (PS) -25725 + (NN) -1415 + (LL) 3764 1D Compatibility (HY) -14800 + (ID) 4200 Total energy: -178590.0 ( -92.44 by residue) QMean score : 0.341

(partial model without unconserved sides chains): PDB file : Tito_2CGW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CGW-query.scw PDB file : Tito_Scwrl_2CGW.pdb: