Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMEKTFIMVKPDGVQRQLIGDILSRFERKGLQLAGAKLMRVTEQMAEKHYAEHQGKPFFGELVEFITSGPVFAMVWEGENVIEVTRQLIGKTNPKEALPGTIRGDYGMFVGKNIIHGSDSLESAEREINIFFKNEELVSYQQLMAGWIY 4UOG Chain:B ((4-150)) --ERTFIAVKPDGVQRGLIGEIIKRFEAKGFKLAGMKYIQASEDLLKQHYIDLADKPFYPGLCKYMSSGPVVAMCWEGTGVVKTARVMMGETRPADSKPGTIRGDFCIEVGRNIIHGSDSVESANKEIALWFKPEELVSWTQTNESWIY

General information: TITO was launched using: RESULT: Template: 4UOG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 671 -69571 -103.68 -473.27 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.88 3D Compatibility (PKB) : -103.68 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.519

(partial model without unconserved sides chains): PDB file : Tito_4UOG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UOG-query.scw PDB file : Tito_Scwrl_4UOG.pdb: