Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKQTIRVELTSTKKPKPDPNQLSFGRVFTDHMFVMDYAADKGWYDPRIIPYQPLSMDPAAMVYHYGQTVFEGLKAYVSEDDHVLLFRPEKNMERLNQSNDRLCIPQIDEEQVLEGLKQLVAIDKDWIPNA-EGTSLYIRPFIIATEPFLGVAASHTYKLLIILSPVGSYYKEGIKPVKIAVESEFVRAVKGGTGNAKTAGNYASSLKAQQVAEEKGFSQVLWLDGIEKKY--IEEVGSMNIFFKI-NG-EIVTPMLNGSILEGITRNSVIALLK-HWGLQVSERKIAIDEVIQAHKDGILEEAFGTGTAAVISPVGELIWQDE-TLSINNGETGEIAKKLYDTITGIQKGAVADEFGWTTEVAALTESK 3UZO Chain:A ((24-358)) -----------------IDWSTLGFSYIRTDLRYLAHWKD-GEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYRCADGSINLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLYLRPFVIGVGDNIGVRTAPEFIFSVFCVPVGPYFKGGLTPTNFITSD-YDRAAPHGTGAAKVGGNYAASLLPGYEAKKRDFADVIYLDPA--THTTIEEAGAANFFAITQDGQKFVTPQS-PSILPSITKYSLLWLAEHRLGLEVEEGDIRIDELGK------FSEAGACGTAAVITPIGGIQHGDDFHVFYSESEPGPVTRRLYDELVGIQYGDKEAPEGWIVKV-------

General information: TITO was launched using: RESULT: Template: 3UZO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1860 -103836 -55.83 -316.57 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -55.83 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_3UZO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UZO-query.scw PDB file : Tito_Scwrl_3UZO.pdb: