Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRLKAISTPVKTD-RLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIEVSQFK--DIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSAPGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNATAAEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLDLVVRLTGSGYQRIFPIITGRLIPRPR 4DMM Chain:B ((29-219)) ------RIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADVSQESEVEALFAAVIERWGRLDVLVNNAGI--TRDTLLLRMKRDDWQSVLDLNLGGVFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRG--ITVNAVAPGFIAT------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4DMM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -53539 for 1549 contacts (-34.6/contact) + 2D Compatibility (PS) -20237 + (NN) -9653 + (LL) 7340 1D Compatibility (HY) -12000 + (ID) 3400 Total energy: -91489.0 ( -59.06 by residue) QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_4DMM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DMM-query.scw PDB file : Tito_Scwrl_4DMM.pdb: