Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTERLLRYFRDKQQDVQSEKTYDTQCPFCSMQCKMQLVE---QTIVTRKKYTAIGIDNPTTQGRLCIKGMNAHQHALNSSRITRPLLK-------KNGEFMPVSWEEALNHIKDQVTMIQTEHGHDAMAVYGSASITNEEAYLLGKFARVGLQTKYIDYNGRLCMSAAATAANQTFGADRGLTNPLSDIPHTRVIILAGTNIAECQPTIMPYFEKAKENGAYFIAIDPRETATTKIADLH---LKIKPGTDAALANGLVKIIIDEQLINEDFIQSRTN----------------------------------GFEELKQHTDSLDLNDIAEQTSVSLVDIRKAAVKFAK-ETSGMLFTARGIEQQTDGTAAVKGFLNMVLITGKIGKPYSGYGAITGQGNGQG-AREHGQKADQLPGYRSIENEEHRAHIAKVWGIHQDELPRK-GVSAYEMMEKINDGDIKGLFLMCSNPAVSSPNANLVKKALRR--LTFFVAIDLFISETAKYADVILPASSYLEDEGTMTNVEGRVTLREASRPCPGEAKHD-WQI----------------ICDLASAL-GKGRY----------------------------FSYTSAEDIFNELREASRGGIADYSGI-SYGRLRREGGIHWPCPESDH--------------PGTGRLFTESFAHPDQKAALSVIPNEPPVPKEKPTADYPLYLTTGRVMSHYLTGVQTRKSAALAARHFESFMEIHPQTAATYNIEDRVLVKIESPRGSITVR--SKLSEQIRKDTVFVPIHWADA-QNVNDLIGEALDPACKMPGFKVCAVRIIPI 1OGY Chain:A ((19-799)) -------------------------CRFCGTGCGVMVGTRDGQVVATHGDTQA-----EVNRGLNCVKGYFLSKIMYGEDRLTTPLLRMKDGVYHKEGEFAPVSWDEAFDVMAAQAKLVLKEKAPEAVGMFGSGQWTIWEGYAASKLMRAGFRSNNLDPNARHCMASAATAFMRTFGMDEPM-GCYDDFEAADAFVLWGSNMAEMHPILWSRLTDRRLSHEH-VRVAVLSTFTHRSSDLSDTPIIFRPGTDRAILNYIAHHIISTGRVNRDFVDRHTNFALGATDIGYGLRPEHQLQLAAKGAADAGAMTPTDFETFAALVSEYTLEKAAEISGVEPALLEELAELYADPDRKWMSLWTMGFNQHVRGVWANHMVYNLHLLTGKISEPGNSPFSLTGQPFACGTAREVGTFAHRLPADMVVTNPEHRAHAEEIWKLPAGLLPDWVGAHAVEQDRKLHDGEINFYWVQVNNNMQAAPNIDQETYPGYRNPENFIVVSDAYPTVTGRAADLVLPAAMWVEKEGAYGNAERRTHFWHQLVEAPGEARSDLWQLMEFSKRFTTDEVWPEEILSAAPAYRGKTLFEVLFANGSVDRFPASDVNPDHANHEAALFGFYPQKGLFEEYAAFGRGHGHDLAPFDTYHEVR---GLHWPVVEGEETRWRYREGFDPYVKPGEGLRF---YGKPDGRAVILGVPYEPPA--ESPDEEFGFWLVTGRVLEHWHSGSMTLRWPELYKAFPGAVCFMHPEDARSRGLNRGSEVRVISRRGEIRTRLETRGRNRMPRGVVFVP--WFDASQLINKVTLDANDPISRQTDFKKCAVKI---

General information: TITO was launched using: RESULT: Template: 1OGY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 4358 -238105 -54.64 -358.05 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -54.64 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.392

(partial model without unconserved sides chains): PDB file : Tito_1OGY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OGY-query.scw PDB file : Tito_Scwrl_1OGY.pdb: