Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKLDEMTAYLPPFLTKLKEMAELLKAEAPEFEKQNNSIFDLTDQLFVTTATWGLERWEKILNVPRESGDTDEIRRLRLISKMSNIPPATYRAIEHALNRFLKNPSAQVRLLPGEYRFKVDIDIDDMQHM--SELIETLENMKPAHLAYTLRAALNEPLQIKDTVILNNRRYRKASELKVGYSVTLNNNEVVLV 1RZR Chain:G ((21-111)) -----------------------------------------------------------------------------RVVNGNPNVKPSTRKKVLETIERLGYRPNAVARGLASKKTTTVGVIIPDISNIFYAELARGIEDIATMY-KYNIILSNSDQNQDKELHLLNN-------------------------

General information: TITO was launched using: RESULT: Template: 1RZR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 187 3418 18.28 38.40 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain G : 0.61 3D Compatibility (PKB) : 18.28 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.207

(partial model without unconserved sides chains): PDB file : Tito_1RZR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RZR-query.scw PDB file : Tito_Scwrl_1RZR.pdb: