Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIEFVKGTIDYVSPQYIVIENGGIGYQI-FTPNPF-IYKERSQETIFTYHHIREDAFSLYGFSTREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIQAIENEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIENLFNHEERLEKQTAETALEEALEALRVLGYAEKEIKKVLPH-LKEEIGLTTDQYVKKALQKLLK 2ZTC Chain:A ((17-210)) MIASVRGEVLEVALDHVVIEAAGVGYRVNATPATLATLRQGTEARLITAMIVREDSMTLYGFPDGETRDLFLTLLSVSGVGPRLAMAALAVHDAPALRQVLADGNVAALTRVPGIGKRGAERMVLELRDKV-------------HAVR----------SPVVEALVGLGFAAKQAEEATDTVLAANHDATTSSALRSALSLLGK

General information: TITO was launched using: RESULT: Template: 2ZTC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 760 6342 8.34 35.63 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 8.34 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_2ZTC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZTC-query.scw PDB file : Tito_Scwrl_2ZTC.pdb: