Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEGKNLTSISECFLLGFSEQLEEQKPLFGSFLFMYLVTVA---GNLLIILVIITDTQLHTPMYFFLANLSLADACFVSTTVPKMLANIQIQSQAISYSGCLLQLYFFMLFVMLEAFLLAVMAYDCYVAICHPLHYILIMSPGLCIFLVSASWIMNALHSLLHTLLMNSLSFCANHEIPHFFCDINPLLSLSCTDPFTNELVIFITGGLTGLICVLCLIISYTNVFSTILKIPSAQGKRKAFSTCSSHLSVVSLFFGTSFCVDFSSPSTHSAQKDTVASVMYTVVTPMLNPFIYSLRNQEIKSSLRKLIWVRKIHSP 3NY8 Chain:A ((40-232)) -------------------------WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMH---WYRATHQEA-----INCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLK

General information: TITO was launched using: RESULT: Template: 3NY8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -176274 for 1282 contacts (-137.5/contact) + 2D Compatibility (PS) -19568 + (NN) -9568 + (LL) 2224 1D Compatibility (HY) -15200 + (ID) 2400 Total energy: -220786.0 ( -172.22 by residue) QMean score : 0.190

(partial model without unconserved sides chains): PDB file : Tito_3NY8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NY8-query.scw PDB file : Tito_Scwrl_3NY8.pdb: