Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPISLPKVRGIYRYSVLMSKITWLNVGGQADILFKPRDIEDLIYLIKNTKLPISVIGATSNMIVRD--------SGIRGITVKLGKEFAYIKYKSNNSIIAGGAALLSNLAYFAGEQQVSGLEFLVGIPGTIGGGIEMNAGAYGSDVASVVQSIKAVNLSDGNLYEFSSKEMGYVYRG----HSLKGQWIFIEAEFKGVSSGHEVI----LHRL-------KEIIN------KKNKSQPVRGKTAGCIFKNP---------------------------RAYQAWKLIDGSGCRGLNNGGAKISKKHCNFLLNYNNATASDLENLGNKVRNTVKDKFNIELEWEIRVLGSH 2Q85 Chain:A ((42-331)) ---------------------------------------------------PVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLH--------VGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGW-LIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGAS

General information: TITO was launched using: RESULT: Template: 2Q85.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -115907 for 1774 contacts (-65.3/contact) + 2D Compatibility (PS) -24906 + (NN) -4608 + (LL) 4312 1D Compatibility (HY) -18000 + (ID) 3450 Total energy: -162559.0 ( -91.63 by residue) QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_2Q85.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q85-query.scw PDB file : Tito_Scwrl_2Q85.pdb: